| Autor: |
Bourke, J. P., Jones, J. L., Fletcher, A., Graham-Brown, R. A. C. |
| Předmět: |
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| Zdroj: |
British Journal of Dermatology; Apr1996, Vol. 134 Issue 4, p705-709, 5p |
| Abstrakt: |
Interleukin 1 (IL-1) has been proposed as a possible mediator in Sweet's syndrome. We examined all cases of Sweet's syndrome (n = 12) presenting to the department over a 10-year period, from 1982 to 1992, for the presence of IL-1 and also assessed the nature of the dermal inflammatory infiltrate in those cases. Staining for IL-1α and IL-1β was stronger in control tissues than in Sweet's syndrome. This may possibly be explained by the release of IL-1α and IL-1β into the dermis in Sweet's syndrome. Contrary to recent reports, we found that neutrophils predominated in all cases examined, although histiocytes were present in increased numbers indicating their possible role in the pathophysiology of Sweet's syndrome. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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