Active vitamin D3 does not suppress recruitment of Go cells following injury.

Autor:	van Bokhoven, M.G.J., de Mare, S., Czarnetzki, B.M., van Erp, P.E.J., Boezeman, J.B.M., van de Kerkhof, P.C.M.
Předmět:	PSORIASIS VITAMIN D FAT-soluble vitamins STEROID hormones DNA replication DNA synthesis FLOW cytometry DIAGNOSTIC use of flow cytometry
Zdroj:	British Journal of Dermatology; Dec1988, Vol. 119 Issue 6, p737-742, 6p
Abstrakt:	The effect of topically applied active vitamin D3 on epidermal regeneration was studied in eight healthy volunteers following sellotape stripping. The mobilization of resting (Go) cells was assessed by means of DNA flow cytometry, using a narrow window in the mid-S phase to monitor the progress of the recruited cells. Although vitamin D3 was applied at a concentration exceeding the range reported to be effective in psoriasis, we were unable to find any effect of active vitamin D3 on Go mobilization in vivo. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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