Autor: |
Alali, Sukaina, Hsu, Jean, Akbar, Abraham, Welch, Robert, Gibbs, Joseph, Pollack, Charles, Fanikos, J, Chebolu, E, Nguyen, Jennifer, Fermann, Gregory, Jivanjee, Mufaddal, Williams, James, Imhoff, Bryan, Rising, Kristin, Isaacs, R, Zhongyang, Teo, Mahan, Charles, Le, Tinh, Rosenblatt, Lauren, Gueye, I |
Předmět: |
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Zdroj: |
Journal of Emergencies, Trauma & Shock; Jan-Mar2021, Vol. 14 Issue 1, p61-71, 11p |
Abstrakt: |
During follow-up, MB versus non-MB patients had, on average, twice as many all-cause hospitalizations (1.1 vs. 0.4 per patient year, P < 0.001), longer total hospital length of stays (7.7 vs. 2.3 days per patient year, P < 0.001), and higher all-cause inpatient ($33,640 vs. $13,671 per patient, P < 0.001) and outpatient ($39,302 vs. $21,640 per patient, P < 0.001) costs. Methods: Adult patients (>=18 years of age) treated with FXaIs (rivaroxaban, apixaban, or edoxaban) who were hospitalized with MB (MB patients) or had no MB hospitalizations (non-MB patients) during January 1, 2015, through April 30, 2018, were extracted from the MarketScan claims databases. Metabolomic Profiling during Diabetic Ketoacidosis and the Pathophysiology of Ketosis-Prone Diabetes Jean W. Hsu, Paras Mehta, Kelly R. Keene, Surya N. Mulukutla, Eunice I. Caducoy, William Peacock, Ashok Balasubramanyam, Farook Jahoor Baylor College of Medicine, Houston, TX, USA Background: Obese patients with ketosis-prone type 2 diabetes ("A-B+ KPD") have increased catabolism of the ketogenic amino acids leucine/isoleucine (Leu/Ile) and impaired ketone oxidation when stable and normoglycemic. Bleeding concern patients had higher mortality (6.3%) than acute hemorrhage patients (0.002% overall, 1.1% for intracranial hemorrhage) but were also older with more comorbidities. [Extracted from the article] |
Databáze: |
Complementary Index |
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