Study of biotransformation of cholesterol 3β-methyl ether by mycobacteria Mycobacterium sp.

Autor: Yaderets, V. V., Karpova, N. V., Stytsenko, T. S., Andryushina, V. A., Kurilov, D. V., Zavarzin, I. V.
Předmět:
Zdroj: Russian Chemical Bulletin; Mar2021, Vol. 70 Issue 3, p533-538, 6p
Abstrakt: The influence of exogenous factors on the selectivity of biotransformation of cholesterol 3β-methyl ether by Mycobacterium sp. was studied. The main product of the microbiological transformation was Δ5-dehydroepiandrosterone 3β-methyl ether. The presence of methyl-β-cyclodextrin in the bacterial growth medium led to a change in the ratio of the reaction products and an increase in the yield of Δ4-androstene-3,17-dione. Aliphatic saturated and unsaturated carboxylic acids were also formed in the course of biotransformation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index