| Autor: |
Li, Xin, Chan, Jasper Fuk-Woo, Li, Kenneth Kai-Wang, Tso, Eugene Yuk-Keung, Yip, Cyril Chik-Yan, Sridhar, Siddharth, Chung, Tom Wai-Hin, Chiu, Kelvin Hei-Yeung, Hung, Derek Ling-Lung, Wu, Alan Ka-Lun, Chau, Sandy Ka-Yee, Liu, Raymond, Lung, Kwok-Cheung, Tam, Anthony Raymond, Cheng, Vincent Chi-Chung, To, Kelvin Kai-Wang, Chan, Kwok-Hung, Hung, Ivan Fan-Ngai, Yuen, Kwok-Yung |
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| Zdroj: |
Infection; Apr2021, Vol. 49 Issue 2, p257-265, 9p, 3 Charts |
| Abstrakt: |
Purpose: To evaluate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in conjunctival secretions from patients without ocular symptoms. Methods: Conjunctival swabs were prospectively collected from laboratory-confirmed Coronavirus disease 2019 (COVID-19) patients without ocular symptoms for reverse transcription-polymerase chain reaction (RT-PCR) and viral culture. Results: A total of 158 conjunctival swabs were obtained from 49 laboratory-confirmed COVID-19 patients. The median duration of illness when the first conjunctival swab was obtained was 10 days (range 2–27 days). Four conjunctival swabs from four different patients (4/49, 8.2%) were positive for SARS-CoV-2 RNA by RT-PCR. The Ct values ranged from 32.7 to 37.7 (mean 35.4). Viral cultures were negative for all four RT-PCR-positive conjunctival swabs. Conclusion: Conjunctival secretions of a minority of COVID-19 patients without ocular symptoms may contain relatively low levels of SARS-CoV-2 RNA, but their infectiousness remains undetermined. Appropriate infection control measures should be implemented during ophthalmological assessment of COVID-19 patients to prevent potential nosocomial transmission of SARS-CoV-2. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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