Interfacial cationization to quicken redox-responsive drug release.

Autor: Zheng, Yaxin, Lei, Jie, Li, Qi, Jin, Xuan, Li, Qingyuan, Li, Yang
Předmět:
Zdroj: Chemical Communications; 3/21/2021, Vol. 57 Issue 23, p2943-2946, 4p
Abstrakt: Interfacial cationization could greatly increase the redox-responsiveness of disulfide bond-linked lipid-drug nanoassemblies (NAs) due to the generation and concentration of ionized thiols at the alkalized NAs' cationic interface. This strategy could be used to prepare redox-ultrasensitive nanocarriers for efficient intracellular drug delivery. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index