| Autor: |
Imamuddin, Syed, Aruna valli, C. Venkata, Kolli, Jagadeesh Reddy, Ramkishanrao, Munde Anant, K. M. K. Reddy P. |
| Předmět: |
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| Zdroj: |
International Archives of Integrated Medicine; Mar2021, Vol. 8 Issue 3, p20-26, 7p |
| Abstrakt: |
Introduction: Hyperlactatemia indicates widespread inadequate tissue perfusion and oxygenation. In patients with critical and severe illnesses, the prolonged presence of lactic acidosis correlates with overall oxygen debt, multi organ dysfunction and mortality. Objective: To determine predictive value of lactate clearance for in-hospital mortality in cardiogenic shock following STEMI and to correlate lactate clearance with TIMI and GRACE risk scores. Materials and methods: Fifty patients of >18 years of age (Mean age 55.76 + 11.22 years, 78% Males) in cardiogenic shock following STEMI were observed between January 2018 to December 2019. Venous blood lactate was done at admission and twelve hours after admission. Lactate clearance (LC) was correlated with in-hospital mortality and with clinical risk scores. Results: Out of fifty patients 17 (34%) died during hospital stay. In-hospital mortality was 89.47% in patients with LC <10% against no mortality in patients with LC >10% (P= 0.000). LC <10% predicted in-hospital mortality with sensitivity of 100%, specificity of 93.93%, PPV of 89.5 and NPV of 100%. Conclusion: Lactate clearance at first twelve hours of admission is a very sensitive and specific test to predict mortality in patients with cardiogenic shock due to STEMI. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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