| Autor: |
Hindsén, Monica, Christensen, Ole B., Gruic, Vinka, Löfberg, Helge |
| Předmět: |
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| Zdroj: |
British Journal of Dermatology; Mar1987, Vol. 116 Issue 3, p351-360, 10p |
| Abstrakt: |
Five patients were each challenged orally with a drug which had previously induced a fixed drug eruption. A positive reaction occurred in all the patients. Punch biopsies were taken 6–12 h, 24 h and 3 weeks after challenge. The specimens were tested with different mouse anti-human monoclonal antibodies to identify T lymphocytes and phenotypic subsets, natural killer cells, B lymphocytes, OKT-6 and HLA-DR-positive cells. T suppressor/cytotoxic cells seemed to play a major role in initiating the flare-up reaction and preserving the cutaneous memory function of the fixed drug eruption. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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