Multi-center study on overall clinical complexity of patients with prolonged disorders of consciousness of different etiologies.
| Autor: | Estraneo, A, Masotta, O, Bartolo, M, Pistoia, F, Perin, C, Marino, S, Lucca, L, Pingue, V, Casanova, E, Romoli, A, Gentile, S, Formisano, R, Salvi, GP, Scarponi, F, De Tanti, A, Bongioanni, P, Rossato, E, Santangelo, A, Diana, AR, Gambarin, M |
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| Předmět: |
RESEARCH
INTENSIVE care units SCIENTIFIC observation REHABILITATION centers EQUIPMENT & supplies CHRONIC diseases CROSS-sectional method LOSS of consciousness MEDICAL cooperation PERSISTENT vegetative state SEVERITY of illness index SYMPTOMS WAKEFULNESS BRAIN injuries PEOPLE with disabilities NEEDS assessment HYPOXEMIA CONSCIOUSNESS disorders COMORBIDITY DISEASE complications |
| Zdroj: | Brain Injury; 2021, Vol. 35 Issue 1, p1-7, 7p |
| Abstrakt: | Aim: to assess overall clinical complexity of patients with acquired disorders of consciousness (DoC) in vegetative state/unresponsive wakefulness syndrome (VS/UWS) vs. minimally conscious state- MCS) and in different etiologies.. Design: Multi-center cross-sectional observational study. Setting: 23 intensive neurorehabilitation units. Subjects: 264 patients with DoC in the post-acute phase: VS/UWS = 141, and MCS = 123 due to vascular (n = 125), traumatic (n = 83) or anoxic (n = 56) brain injury. Main Measures: Coma Recovery Scale-Revised, and Disability Rating Scale (DRS); presence of medical devices (e.g., for eating or breathing); occurrence and severity of medical complications. Results: patients in DoC, and particularly those in VS/UWS, showed severe overall clinical complexity. Anoxic patients had higher overall clinical complexity, lower level of responsiveness/consciousness, higher functional disability, and higher needs of medical devices. Vascular patients had worse premorbid clinical comorbidities. The two etiologies showed a comparable rate of MC, higher than that observed in traumatic etiology. Conclusion: overall clinical complexity is significantly higher in VS/UWS than in MCS, and in non-traumatic vs. traumatic etiology. These findings could explain the worse clinical evolution reported in anoxic and vascular etiologies and in VS/UWS patients and contribute to plan patient-tailored care and rehabilitation programmes. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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