Effect of topical calcipotriol on congenital ichthyoses.

Autor: Lucker, G. P. H., Van De Kerkhof, P. C. M., Van Dïjk, M. R., Steijlen, P. M.
Předmět:
Zdroj: British Journal of Dermatology; Oct1994, Vol. 131 Issue 4, p546-550, 5p
Abstrakt: We investigated the clinical efficacy of topically applied calcipotriol in six patients with congenital ichthyosis. using a double-blind, bilaterally paired, comparative approach. Unilateral improvement, in favour of the calcipotriol-treated side, was observed in three patients with lamellar ichthyosis. A beneficial response was also observed in a patient with bullous ichthyotic erythroderina of Brocq. No clinical side-effects or laboratory anomalies were observed. This study indicates that calcipotriol constitutes a new and promising approach in alleviating disorders of keratinization characterized by hyperproliferation. other than psoriasis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index