Synthesis of Fused Pyrimido[1,6- a ]indolones via Rhodium(III)-Catalyzed Cascade Annulations.

Autor: Raji Reddy, Chada, Bodasu, Srinivas, Mallesh, Kathe, Prapurna, Y. Lakshmi
Předmět:
Zdroj: Synthesis; 2021, Vol. 53 Issue 6, p1127-1136, 10p
Abstrakt: A novel method for the synthesis of fused pyrimido[1,6- a ]-indolone derivatives by annulation of 2-alkynylaryl aldehydes/2-alkynyl-arylidene ketones with N -(pivaloyloxy)-1 H -indole-1-carboxamide catalyzed by rhodium has been accomplished. The reaction proceeds through C–H activation based annulation with alkyne moiety followed by addition of nitrogen on to aldehyde/activated alkene to give the products in moderate to good yields. Highly fluorescent dipyrrinone analogues could be synthesized from the derived products. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index