A case of mixed neuroendocrine non-neuroendocrine neoplasm of the distal bile duct with biliary intraepithelial neoplasia.

Autor: Kaino, Miyuki, Kaino, Seiji, Goma, Wakana, Hideura, Eizaburo, Hitosugi, Tomoki, Harima, Yohei, Urata, Yohei, Nakamura, Yohei
Zdroj: Clinical Journal of Gastroenterology; Feb2021, Vol. 14 Issue 1, p297-303, 7p
Abstrakt: A 72-year-old man with obstructive jaundice, diagnosed with distal biliary carcinoma, underwent pylorus-preserving pancreaticoduodenectomy. The patient was histopathologically and immunohistochemically diagnosed with mixed neuroendocrine non-neuroendocrine neoplasm. Pathological examination revealed that the well-differentiated adenocarcinoma components occupied the superficial portion of the bile duct and the neuroendocrine carcinoma components were located in the deeper portion of the bile duct. Pathological examination showed that a portion of the biliary intraepithelial neoplasia arose from the proximal bile duct and then extended to the gallbladder. The patient was administered tegafur/gimeracil/oteracil as adjuvant chemotherapy, and the lesion did not recur for 6 months postoperatively. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index