A Red-Emissive AIE Probe for Targeting Mitochondria in Living Cells.

Autor: Xiao, Lufei, Xiao, Rui, Xu, Bingsong, Chen, Hao, Wang, Hui
Zdroj: Australian Journal of Chemistry; 2021, Vol. 74 Issue 2, p151-156, 6p
Abstrakt: A novel compound has been synthesised and characterised by various spectroscopic techniques. Analysing the crystal structures of the compound shows that multiple molecular interactions exist. The compound exhibits distinct aggregation-induced emission activity in EtOH/H2O accompanying a 2-fold enhancement of fluorescence intensity at ~609 nm. In addition, the cytotoxicity assay and confocal microscopy imaging show that the compound is hypotoxic and can be used as a fluorescent labelling dye in the near-infrared region to track mitochondria in living cells. A novel compound has been synthesised and characterised, which exhibits distinct aggregation-induced emission activity in EtOH/H2O and can be used as a fluorescent labelling dye in the near-infrared region to track mitochondria in living cells. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index