| Autor: |
MEMON, KHALID YOUSUF, UJJAN, IKRAM DIN, YOUSUF, NAILLA, ALA, SYED HASAN, RUSTAMANI, SHABNAM, SHAIKH, FOZIA, CHANG, ABID HUSSAIN, MAHRUKH, SUHA |
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| Zdroj: |
Journal of Clinical & Diagnostic Research; Nov2020, Vol. 14 Issue 11, p42-44, 3p |
| Abstrakt: |
Introduction: Pre-Eclampsia (PE) is the common multisystem disorder which complicates the pregnancies 3-8% and a major cause of morbidity and mortality throughout the world. Aim: To determine the correlation of placental growth factor with PE in mid trimester of pregnancy at Liaquat University of Medical and Health Sciences Jamshoro. Materials and Methods: This Case-Control study was performed at Pathology Department with Department of Obstetrics and Gynaecology, Liaquat University of Medical and Health Sciences (LUMHS) Jamshoro/Hyderabad, during 12 months, from 6th February, 2017 to 5th February 2018. Pregnant women with mid trimester were enrolled in the study. Group A included females with PE, while Group B were normotensive females of same gestation. Their blood sample were collected and stored at -80°. Level of placental growth factor was measured on Elecsys system. Data was analysed via Statistical Package for the Social Sciences (SPSS) version 20. Results: Total 384 PE females were selected and 50 females without hypertension were studied as control. Mean age of patients was 27.46±3.91 years. No significant variance was seen between mean of gestational age of patients and normal pregnant females; p-value 0.346. Mean of placental growth factor was insignificantly decreased 35.21±31.68 pg/mL among patients in contrast to normal women as 47.23±56.13 pg/mL, p=0.081. A negative correlation was found between blood pressure and placental growth factor, r-values -0.004 and -0.001, respectively. Conclusion: It was concluded that serum placental growth factor was the poor marker for PE, as it showed weak negative correlation with PE. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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