Transfusion transmissible pathogens are prevalent in healthy cats eligible to become blood donors.

Autor: Mesa‐Sanchez, I., Ferreira, R. R. F., Cardoso, I., Morais, M., Flamínio, M., Vieira, S., Gopegui, R. R., Matos, A. J. F.
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Zdroj: Journal of Small Animal Practice; Feb2021, Vol. 62 Issue 2, p107-113, 7p
Abstrakt: Objectives: This study aims to determine the prevalence of subclinical infectious agents considered core pathogens for worldwide screening in healthy, client‐owned, indoor cats eligible to become blood donors in Spain and Portugal. Materials and Methods: Blood samples of healthy, indoor, domestic cats selected to be potential blood donors were tested for feline leukaemia virus antigens, feline immunodeficiency virus antibodies and polymerase chain reactions for Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, Candidatus Mycoplasma turicensis, feline leukaemia virus provirus, Leishmania spp. and Bartonella spp. Not all donors were tested for all agents. Results: Overall, 5105 healthy indoor cats were tested and 8.1% (414/5105) had at least one subclinical infectious agent that is transmissible through blood product transfusion. 1.5% (77/5105) were positive for feline leukaemia virus antigens and 2.9% (148/5105) were positive for feline immunodeficiency virus antibodies, therefore they were excluded as donors. The overall prevalence of haemoplasmas in feline leukaemia virus and feline immunodeficiency virus SNAP‐negative feline blood donors was 3.7% (181/4880) [1.3% (63/4880) were positive for Mycoplasma haemofelis; 2.3% (112/4880) to Candidatus Mycoplasma haemominutum and 0.12% (6/4880) to Candidatus Mycoplasma turicensis]. The prevalence of feline leukaemia provirus was 5.2% (9/173) and of Bartonella spp. was 0.2% (2/1122). None of the 173 cats were positive for Leishmania spp. Clinical Significance: The prevalence of many transfusion transmissible pathogens was relatively high in this healthy, client‐owned, indoor cats eligible to become blood donors. Performing an extended screening panel that includes at least polymerase chain reactions for Mycoplasma haemofelis, Candidatus Mycoplasma haemominutum, Candidatus Mycoplasma turicensis, feline leukaemia virus provirus, and Bartonella spp., in addition to feline leukaemia virus antigens and feline immunodeficiency virus antibodies, is recommended in pet blood banks from analogous regions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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