| Autor: |
More, Bhagirath P., Soni, T. V., Salunke, Mayuri |
| Předmět: |
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| Zdroj: |
Indian Journal of Basic & Applied Medical Research; Dec2020, Vol. 10 Issue 1, p86-92, 7p |
| Abstrakt: |
Introduction: High grade gliomas display extensive morphological and molecular heterogenicity, and thus may reflect their origin from different population of astrocytes, and possibly from oligodendrocytic and ependymal cell lineages. Material and methods: The present study was conducted in the department of neurosurgery, NHL municipal medical college & V S Hospital - Ahmedabad, Gujarat. In present study all patients who underwent craniotomy and excision / decompression of high grade glioma (glioblastoma multiforme & its variants) during the period of october 2014 to January 2017 were included for the prospective analysis. Results: By frontal approach, 18% patients by parieto-occipital & 12% patients by temporo-parietal craniectomy/craniotomy approach. 8% patients were operated by fronto-parietal & another 8% patients by parietal, 4% by temporal approach. SuboccipitalCraniectomy was done in 2 patients. Conclusion: Median survival in our study was 12.7 months (51weeks) with maximum survival of those patient who were younger (<35 Yr), good preop condition with KPS score (>80), having near total resection and postoperatively took both radiotherapy and chemotherapy. Adjuvant chemotherapy following radiotherapy provided survival advantage 3.36 months in our study. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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