| Autor: |
Llamas‐Velasco, M., Reolid, A., Sanz‐García, A., Alonso‐Guirado, L., García‐Martínez, J., Sánchez‐Jiménez, P., Muñoz‐Aceituno, E., Daudén, E., Abad‐Santos, F., Ovejero‐Benito, M.C. |
| Předmět: |
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| Zdroj: |
Journal of the European Academy of Dermatology & Venereology; Feb2021, Vol. 35 Issue 2, pe161-e163, 3p |
| Abstrakt: |
Psoriasis prevalence has been traditionally considered equal in men and women.1 Nonetheless, recent studies have shown that psoriasis also presents sex differences, with a higher severity and prevalence in males.2 Therefore, we hypothesized that these differences may be partially explained by sex-specific methylation differences. To elucidate this, we propose to explore sex-associated differentially methylated CpG sites (DMS) in psoriasis datasets from DNA methylation arrays obtained from the repository Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo/). The global analysis combining all the data sets showed that the number of psoriasis-related genes common to the three data sets was 2455 in females and 6646 in males. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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