A Catalytic One-Pot Synthesis of Indolyl Cyclobutanones.

Autor: Porcu, Stefania, Rodriguez, Carla Aira, Frongia, Angelo, Secci, Francesco
Předmět:
Zdroj: Synthesis; 2021, Vol. 53 Issue 5, p925-932, 8p
Abstrakt: A general strategy for the synthesis of indolyl cyclobutanones via a tandem Brønsted acid catalyzed 2-hydroxycyclobutanone activation–indole nucleophilic addition has been exploited. The procedure leads to a wide range of 2- and 3-functionalized indole derivatives in good to high yields with broad substrate scope. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index