Anti-phage serum antibody responses and the outcome of phage therapy.

Autor: Łusiak-Szelachowska, M., Międzybrodzki, R., Fortuna, W., Borysowski, J., Górski, Andrzej
Zdroj: Folia Microbiologica; 2021, Vol. 66 Issue 1, p127-131, 5p
Abstrakt: We examined the appearance of serum anti-phage antibodies in 25 patients with chronic sinusitis treated with phage therapy (PT). Approximately 30% of patients with weak antibody responses responded positively to PT, which was similar to the results of treatment achieved in a group of patients with high antibody production. In addition, there was no correlation between antibody level and the outcome of PT. These data, derived from a homogenous group of patients, confirm our earlier findings suggesting that the prognostic significance of serum anti-phage antibodies for the outcome of PT should be determined by relevant clinical trials. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index