Morphological and Histological Study on Thyroid Gland Toxicity in Male Rats Exposed to Mercury.

Autor: Ali, Sawsan A.
Předmět:
Zdroj: Indian Journal of Forensic Medicine & Toxicology; Oct-Dec2020, Vol. 14 Issue 4, p2723-2728, 6p
Abstrakt: The present study investigated the effect of heavy metals (Mercury chloride) on the morphological and histological feature of the thyroid gland. Rattus norvegicus male rats were selected for experimental use. the rats given doses of Hg salts (3mg/kg, Ip.3times weekly for 4 week) HgcL2 admin is tration altered the body weight, thyroid weight, length and width of thyroid gland. Morphologically, the thyroid gland was consisted of two labs of reddish brown in color, the lobes were located on ventral Lateral side of trachea connected caudally with isthmus. While the thyroid gland treated rats recorded changes in color (pale), swollen and enlarged. histologically, the architectural cellular structure gland of the thyroid gland of exposed rats recorded variations in the follicular thyroid, congested blood vessels and depletion of para follicular cells in the rats treated to Hg in a comparison to that of the control rats. This signify that animals exposed to Hg could at a risk of thyroid gland. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index