| Autor: |
Moreno-Peral, Patricia, Conejo-Cerón, Sonia, de Dios Luna, Juan, King, Michael, Nazareth, Irwin, Martín-Pérez, Carlos, Fernández-Alonso, Carmen, Ballesta-Rodríguez, María Isabel, Fernández, Anna, Aiarzaguena, José María, Montón-Franco, Carmen, Bellón, Juan Ángel |
| Předmět: |
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| Zdroj: |
British Journal of General Practice; Feb2021, Vol. 71 Issue 703, pe95-e104, 10p |
| Abstrakt: |
Background: In the predictD-intervention, GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%, although the results were not statistically significant.Aim: To determine whether the predictD-intervention is effective at preventing anxiety in primary care patients without depression or anxiety.Design and Setting: Secondary study of a cluster randomised trial with practices randomly assigned to either the predictD-intervention or usual care. This study was conducted in seven Spanish cities from October 2010 to July 2012.Method: In each city, 10 practices and two GPs per practice, as well as four to six patients every recruiting day, were randomly selected until there were 26-27 eligible patients for each GP. The endpoint was cumulative incidence of anxiety as measured by the PRIME-MD screening tool over 18 months.Results: A total of 3326 patients without depression and 140 GPs from 70 practices consented and were eligible to participate; 328 of these patients were removed because they had an anxiety syndrome at baseline. Of the 2998 valid patients, 2597 (86.6%) were evaluated at the end of the study. At 18 months, 10.4% (95% CI = 8.7% to 12.1%) of the patients in the predictD-intervention group developed anxiety compared with 13.1% (95% CI = 11.4% to 14.8%) in the usual-care group (absolute difference = -2.7% [95% CI = -5.1% to -0.3%]; P = 0.029).Conclusion: A personalised intervention delivered by GPs for the prevention of depression provided a modest but statistically significant reduction in the incidence of anxiety. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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