| Autor: |
Hudson-Peacock, M. J., Diffey, B. L., Farr, P. M. |
| Předmět: |
|
| Zdroj: |
British Journal of Dermatology; Mar1994, Vol. 130 Issue 3, p361-365, 5p |
| Abstrakt: |
An in vitro technique was used to measure the monochromatic protection factors of all emollients available on prescription. The action spectra for ultraviolet erythema and erythema in psoralen-sensitized skin were used to calculate, for each emollient, erythema protection factors relevant to UVB phototherapy and psoralen photochemotherapy, respectively. Of the 40 products tested, 22 (55%) had a UVB erythema protection factor > 1.2 at an application density of 2 μl/cm2, and 31 (78%) at an application density of 4 μl/cm2. Fewer products, 25% at 2 μl/cm2 and 50% at 4 μl/cm2, had a psoralen erythema protection factor > 1.2. A protection factor of 1 2 is equivalent to a reduction in ultraviolet dose of 17%, and is thus likely to be of clinical importance. These results allow a choice of emollient products which may improve response by increasing transmission of radiation through psoriasis scale without a concomitant decrease in transmission due to a sunscreening action. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text