| Autor: |
Mikami, Ryuichi, Tanaka, Eiji, Murakami, Teppei, Ishida, Satoshi, Matsui, Yugo, Horita, Kenta, Yamada, Masaki, Nitta, Takashi, Mise, Masahiro, Harada, Takehisa, Takeo, Masahiko, Arii, Shigeki |
| Předmět: |
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| Zdroj: |
Surgery Today; 2021, Vol. 51 Issue 2, p219-225, 7p |
| Abstrakt: |
Purpose: It remains unclear whether laparoscopic gastrectomy (LG) for gastric cancer is a suitable treatment for very elderly (VE) patients. We aimed to assess the safety and feasibility of LG for gastric cancer in VE patients. Methods: We reviewed 226 consecutive patients who underwent LG between January 2010 and December 2016. We compared VE patients (age ≥ 80, n = 38) with non-elderly patients (age ≤ 79, n = 188). Results: An ASA-PS score ≥ 2 was more common in VE group (86.8 vs. 48.9%; P < 0.01). There were no significant differences in the operating time, blood loss, postoperative hospital stay, or postoperative morbidity between the groups. The 3-year survival rate and 3-year disease-specific survival rate were lower in the VE group (53.7 vs. 85.6%; P < 0.0001, 78.5 vs. 92.4%; P = 0.0116). A univariate analysis showed that PS scores ≥ 2, Charlson comorbidity index ≥ 4, and pN stage were independent predictors of decreased overall survival rates in the VE group. A multivariate analysis showed total gastrectomy, a Charlson comorbidity index ≥ 4, and the pN stage to be independent predictors in the VE group. Conclusion: LG for gastric cancer is, thus, considered to be safe for patients aged 80 years or older. Total gastrectomy, a Charlson comorbidity index ≥ 4, and the pN stage were independent risk factors for a poor prognosis in these patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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