Sensitivity of nasopharyngeal, oropharyngeal, and nasal wash specimens for SARS-CoV-2 detection in the setting of sampling device shortage.

Autor:	Calame, Adrien, Mazza, Léna, Renzoni, Adriana, Kaiser, Laurent, Schibler, Manuel
Předmět:	COVID-19 SARS-CoV-2 RESPIRATORY infections
Zdroj:	European Journal of Clinical Microbiology & Infectious Diseases; 2021, Vol. 40 Issue 2, p441-445, 5p
Abstrakt:	In the context of an unprecedented shortage of nasopharyngeal swabs (NPS) or sample transport media during the coronavirus disease 2019 (COVID-19) crisis, alternative methods for sample collection are needed. To address this need, we validated a cell culture medium as a viral transport medium, and compared the analytical sensitivity of SARS-CoV-2 RT-PCR in nasal wash (NW), oropharyngeal swab (OPS), and NPS specimens. Both the clinical and analytical sensitivity were comparable in these three sample types. OPS and NW specimens may therefore represent suitable alternatives to NPS for SARS-CoV-2 detection. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink