Core‐binding factor acute myeloid leukemia with inv(16): Older age and high white blood cell count are risk factors for treatment failure.

Autor:	Ustun, Celalettin, Morgan, Elizabeth A., Ritz, Ethan M, Vestergaard, Hanne, Pullarkat, Sheeja, Kluin, Philip M., Ohgami, Robert, Baughn, Linda B., Kim, Young, Ku, Nam K., Czuchlewski, David, Boe Møller, Michael, Schiefer, Ana‐Iris, Mrózek, Krzysztof, Horny, Hans‐Peter, George, Tracy I., Kielsgaard Kristensen, Thomas, Beck, Todd, Nathan, Sunita, Arana Yi, Cecilia
Předmět:	ACUTE myeloid leukemia treatment MORTALITY risk factors AGE distribution CHROMOSOME abnormalities CONFIDENCE intervals MEDICAL cooperation MULTIVARIATE analysis GENETIC mutation RESEARCH RISK assessment SURVIVAL analysis (Biometry) TIME DISEASE relapse ACUTE myeloid leukemia TREATMENT effectiveness RECEIVER operating characteristic curves DESCRIPTIVE statistics KAPLAN-Meier estimator LEUKOCYTE count
Zdroj:	International Journal of Laboratory Hematology; Feb2021, Vol. 43 Issue 1, pe19-e25, 7p
Abstrakt:	The article discusses research which investigated the risk factors for treatment failure in patients with core-binding factor (CBF) and acute myeloid leukemia (AML). Topics explored include the demographic and laboratory characteristics of patients with CBF-AML, the analysis of event-free survival (EFS), disease-free survival (DFS), and overall survival (OS) data, and the reported link between high white blood cell count and poor DFS.
Databáze:	Complementary Index
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