| Autor: |
Leoni, C., Guerriero, C., Onesimo, R., Coco, V., Di Ruscio, C., Acampora, A., Esposito, I., Romano, A., Tartaglia, M., Genuardi, M., Zampino, G. |
| Předmět: |
|
| Zdroj: |
Journal of the European Academy of Dermatology & Venereology; Jan2021, Vol. 35 Issue 1, pe83-e85, 3p |
| Abstrakt: |
The prevalence of nevi was >=50% in all subgroups, regardless of age; 100% of patients carrying I BRAF i (17), I HRAS i (16), I MEK1/2 i (4) and I RIT1 i variants (1) showed nevi. Univariate analysis detected a significantly lower prevalence of nevi and atypical nevi in patients with NF1 ( I P i = 0.05 and I P i = 0.04, respectively). Our conclusion is that RASopathies are associated with increased risk of nevi regardless of the underlying genetic defect, with the highest number of both typical and atypical nevi in patients carrying I BRAF i and I HRAS i variants. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text