| Autor: |
Safin, Ruslan R., Razumov, Evgeny Y., Baigildeeva, Ekaterina I., Safina, Albina V., Gubernatorov, Valeriy V. |
| Předmět: |
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| Zdroj: |
Proceedings of the International Multidisciplinary Scientific GeoConference SGEM; 2020, p637-644, 8p |
| Abstrakt: |
Chaga is a perennial parasitic fungus of the Hymenochaetaceae family that lives on the bark of aged birch trees. Chaga contains a comprehensive set of substances that are essential for humans. In this context, the Chaga mushroom is widely used in the pharmaceutical industry. Chaga containing drugs are generally used as antiinflammatory and restorative. Chaga can also be used as part of the complex treatment of tumors of various localization, diseases of the gastrointestinal tract, it helps to mobilize the body's defenses by affecting metabolic processes. In the paper analyses the way the method of grinding of plant raw materials might influence the quality of the resulting drugs, including the sustaining the biological activity. The authors carried out a comparative analysis of the results of extraction of samples obtained by conventional grinding and cryogenic grinding in order to determine the effect of cryogenic grinding of chaga on the content of biologically active substances in it. The extraction of crushed raw materials was carried out with water (for organic acids), as well as ethanol and methanol (for other components) according to traditional methods. To determine ceresins insoluble in water and alcohols, 5 ml per 50 ml of benzene was added to the extract gross volume. Analysis of aqueous and alcoholic extracts of samples obtained by conventional grinding and cryogenic grinding was carried out by high performance liquid chromatography and atomic absorption spectrometry. The authors consider the use of cryogenic grinding when receiving drugs from the Chaga fungus reasonable taking into account the advantages of the product obtained from cryogenic crushed raw materials, including the preservation of its biological value, the increase in bioavailability of biologically active substances and the improvement of their adoption by human body. This will allow the preservation of its biologically active substances, that are widely used both in phyto- and fungotherapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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