Uric acid level as a biomarker in heart failure patients in a rural population attending tertiary care hospital in Chengalpattu District, Tamil Nadu.

Autor: Vigneshvar, C. N. Sai, Arumugam, E., Appandraj, S.
Předmět:
Zdroj: International Archives of Integrated Medicine; Dec2020, Vol. 7 Issue 12, p57-63, 7p
Abstrakt: Introduction: It is all around accepted that Heart Failure is a complex clinical condition that can result from any structural or functional cardiovascular issues that hinder the capacity of ventricles to fill up with or eject blood. Coronary artery disease represents a significant part of patients with chronic Heart failure. Heart failure is the end phase of all diseases of the heart and is a significant reason for morbidity and mortality. Aim of the study: To analyze the serum uric acid level in in heart failure patients. Materials and methods: It was a retrospective conducted in the General Medicine and Cardiology Department of Karpaga Vinayaga Medical College, Chengalpattu district, Tamil Nadu from January 2020 to April 2020. The study was conducted on all patients with documented evidence of heart failure and heart failure treatment for at least one month. Patients of both sex aged between 20 to 80 years, patients with Heart failure both with preserved and decreased EF, and patients with Heart failure of at least 1-month duration were included in our study. The privacy and confidentiality of the patient were maintained. Informed consent was taken from the patient for the study. Results: The mean age of the participants was 56.08±8.48 years. The age ranges from 43 years to 76 years. An equal number of males and females participated in our study. Overall co-morbidities present were CAD (62%), RHD (28%), and COPD (10%). Diabetes and hypertension were found among 80% and 78% respectively. Smoking was found among 42% and alcohol among 26% respectively. NYHA grading was done, there were 28% in grade 2 followed by 62% in grade 3 and 10% in grade 4. Dyslipidemia was found among 48% of study participants. The mean uric acid levels were 7.12 mg. Conclusion: It has been observed that in a clinical condition like hypoxemia there is an increase in the serum Uric acid level. The objective of our study was to find out the relationship between serum uric acid levels in the severity of Heart failure. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index