Fluctuating plasmacytosis in an immunocompetent woman leading a diagnosis of plasmablastic lymphoma.

Autor: Debord, Camille, Bourcier, Jessie, Subiger, François, Leclair, François, Touzeau, Cyrille, Gastinne, Thomas, Moreau, Anne, Theisen, Olivier, Godon, Catherine, Robillard, Nelly, Le Bris, Yannick, Béné, Marie C, Wuillème, Soraya
Předmět:
Zdroj: Annals of Hematology; 2021, Vol. 100 Issue 1, p285-287, 3p
Abstrakt: Dear Editor, Plasmablastic lymphoma (PBL), according to the WHO classification of tumors, is a very aggressive non-Hodgkin lymphoma characterized by a diffuse proliferation of immunoblastic to plasmacytic large cells in the peripheral blood with a CD20-negative plasmacytic phenotype [[1]]. The patient was addressed in hematology for a suspicion of plasma cell leukemia after detection of 26% circulating plasma cells in a preoperative complete blood count (CBC). Flow cytometry disclosed 8% of nucleated cells expressing CD38, CD138, CD19, CD27, and cytoplasmic light-chain restriction, lacking CD20 and CD22 consistent with plasma cells (Fig. [Extracted from the article]
Databáze: Complementary Index