Терапевтични затруднения при болестта на Wilson - клиничен случай.

Autor: Кофинова, Д., Шентова-Енева, Р., Байчева, М., Хаджийски, П., Янева, П.
Zdroj: Pediatria; 2020, Vol. 60 Issue 4, p55-56, 2p
Abstrakt: Wilson’s disease is a rare autosomal recessive disorder characterized by accumulation of copper. The treatment is based on the use of chelating agents, which aim to increase the urine excretion of copper. First drug of choice is D-penicillamine. Treatment with D-penicillamine should be strictly monitored, because it can cause early and late side reactions. We report a case of a 13-year-old girl with Wilson’s disease treated with D-penicillamine. The patient suffered from temperature and skin rash after initiating therapy. D-penicillamine was successfully changed with trientine hydrochloride and girl is feeling well. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index