Oral focal mucinosis: A multi‐institutional study and literature review.

Autor: Silva Cunha, John Lennon, Leite, Amanda Almeida, Castro Abrantes, Thamiris, Vervloet, Lorena Passoni, Lima Morais, Thayná Melo, Oliveira Paiva Neto, Gerson, Kimura, Tatiana Nayara Libório, Ferreira, Sônia Maria Soares, Albuquerque‐Júnior, Ricardo Luiz Cavalcanti, Abrahão, Aline Corrêa, Romañach, Mario José, Benevenuto de Andrade, Bruno Augusto, Almeida, Oslei Paes, Soares, Ciro Dantas
Předmět:
Zdroj: Journal of Cutaneous Pathology; Jan2021, Vol. 48 Issue 1, p24-33, 10p, 4 Color Photographs, 2 Charts
Abstrakt: Background: Oral focal mucinosis (OFM) is a rare benign condition of unknown etiology, considered the oral counterpart of cutaneous focal mucinosis. We report the clinicopathologic features of 21 cases of OFM in conjunction with a review of the literature. Methods: Clinical data were collected from the records of five oral and maxillofacial pathology services. All cases were evaluated by hematoxylin and eosin staining, histochemistry, and immunohistochemistry (vimentin, S‐100, α‐SMA, CD34, and mast cell). Results: The series comprised 14 females (66.7%) and seven males (33.3%), with a mean age of 48.2 ± 20.7 years (range: 8‐77 years) and a 2:1 female‐to‐male ratio. Most of the lesions affected the gingiva (n = 6, 28.6%) and presented clinically as asymptomatic sessile or pedunculated nodules with fibrous or hyperplasic appearance. All cases were negative for S‐100 protein, CD34, and α‐SMA and positive for Alcian blue staining. Conservative surgical excision was the treatment in all cases, and there was only one recurrence. Conclusion: OFM is a rare benign disorder that is often clinically misdiagnosed as reactive lesions or benign proliferative processes. Dermatologists and pathologists should consider OFM in the differential diagnosis of soft tissue lesions in the oral cavity, mainly located in the gingiva. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje