Porous hematite nanostructures as drug carriers for biodegradable implants.

Autor: Lozhkomoev, A. S., Kazantsev, S. O., Bakina, O. V., Rubtsov, K. V., Panin, Victor E, Fomin, Vasily M
Předmět:
Zdroj: AIP Conference Proceedings; 2020, Vol. 2310 Issue 1, p1-4, 4p
Abstrakt: The present study deals with porous hematite nanostructures as antimicrobial drug delivery systems. Obtained nanoparticles have been analyzed by Transmission Electron Microscopy (TEM) and X-Ray Diffraction analysis. Porous ellipsoidal particles with a size range of 50–200 nm, which consist of 2–10 nm fragments, were observed. Drug adsorption onto the hematite nanostructures surface has been examined using penicillin and vancomycin as a model systems. Obtained adsorption isotherms represent weak interaction between adsorbate and adsorbent. The maximum adsorption capacities of penicillin and vancomycin were 8 and 6 mg/g respectively. The results suggest that synthesized hematite nanostructures could be used as drug carriers into Fe-Fe2O3 implants. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index