Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay.

Autor: Ly, Vo Trieu, Thanh, Nguyen Tat, Thu, Nguyen Thi Mai, Chan, Jasper, Day, Jeremy N, Perfect, John, Nga, Cao Ngoc, Chau, Nguyen Van Vinh, Le, Thuy
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Zdroj: Open Forum Infectious Diseases; Nov2020, Vol. 7 Issue 11, p1-4, 4p
Abstrakt: Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture–negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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