| Autor: |
Mascitti, Hélène, Bonsang, Benjamin, Dinh, Aurélien, Assan, Florence, Perronne, Véronique, Leblanc, Thibault, Duran, Clara, Bouchand, Frédérique, Matt, Morgan, Gal, Aurélie Le, Thanh, Julia N'guyen Van, Lanore, Aymeric, Jacob, Louis, Kiavue, Nicolas, Siméon, Soline, Bessis, Simon, Truchis, Pierre de, Landowski, Stéphanie, Davido, Benjamin, Moreau, Frédérique |
| Předmět: |
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| Zdroj: |
Open Forum Infectious Diseases; Nov2020, Vol. 7 Issue 11, p1-12, 12p |
| Abstrakt: |
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a current pandemic worldwide. This virus can reach all organs and disturbs the immune system, leading to a cytokine storm in severe forms. We aimed to report cutaneous features among coronavirus disease 2019 (COVID-19) hospitalized patients. Methods We performed a cross-sectional study on 1 given day among all patients hospitalized in acute care for COVID-19 and included all patients with cutaneous features. Follow-up 48 hours later was obtained. Results Among 59 adult patients hospitalized on the day of the study in an infectious diseases ward for SARS-CoV-2 infection who were confirmed by molecular assay and/or radiological findings (computed tomography scan), 40 were included. Several cutaneous manifestations were found: macular exanthema (80%), face edema (32%), livedo (13%), urticarial rash (8%), purpura (5%), oral lichenoid lesions (33%), and conjunctivitis (18%). Cutaneous biopsy was performed in 17 patients. Histological findings showed mast cell hyperplasia (100%), superficial perivascular infiltrate of lymphocytes (94%), and superficial edema (47%) consistent with capillary leak. Conclusions Various dermatological signs can be encountered during COVID-19. A macular rash was the most frequent. All cutaneous features could be related to a vascular leak process. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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