Bypassing TBI: Metabolic Surgery and the Link between Obesity and Traumatic Brain Injury—a Review.

Autor:	McGlennon, T. W., Buchwald, J. N., Pories, Walter J., Yu, Fang, Roberts, Arthur, Ahnfeldt, Eric P., Menon, Rukmini, Buchwald, Henry
Předmět:	BRAIN injuries TYPE 2 diabetes OBESITY WEIGHT loss BARIATRIC surgery GASTRIC bypass GASTRIC banding
Zdroj:	Obesity Surgery; 2020, Vol. 30 Issue 12, p4704-4714, 11p
Abstrakt:	Obesity is a common outcome of traumatic brain injury (TBI) that exacerbates principal TBI symptom domains identified as common areas of post-TBI long-term dysfunction. Obesity is also associated with increased risk of later-life dementia and Alzheimer's disease. Patients with obesity and chronic TBI may be more vulnerable to long-term mental abnormalities. This review explores the question of whether weight loss induced by bariatric surgery could delay or perhaps even reverse the progression of mental deterioration. Bariatric surgery, with its induction of weight loss, remission of type 2 diabetes, and other expressions of the metabolic syndrome, improves metabolic efficiency, leads to reversal of brain lesions seen on imaging studies, and improves function. These observations suggest that metabolic/bariatric surgery may be a most effective therapy for TBI. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink