Utility of Endocervical Sampling at Time of Colposcopy when Referral Cytology Is Low Grade or Better.

Autor: Pierson, Rebecca C., Johnson, Brittany E., Voirol, Jenna R., Kasper, Kelly M.
Zdroj: Reproductive Sciences; Jan2020, Vol. 27 Issue 1, p55-60, 6p
Abstrakt: The utility of endocervical sampling at the time of colposcopic examination after less than high-grade screening Papanicolaou smear is unknown. To address this question, we performed a retrospective review using a colposcopy patient care database maintained at our urban academic medical center. We examined the prevalence of high-grade dysplasia in endocervical samples, the prevalence of high-grade dysplasia in directed cervical biopsies, and the correlations between high-grade endocervical dysplasia and patient factors of age and time to colposcopy. A total of 3026 patient records met inclusion criteria. Mean age at the time of colposcopy was 30 ± 9 years with a range of 21–75 years. The mean time to colposcopy was 96 ± 90 days with a range of 4–1207 days. There was no difference in mean age or days to colposcopy in women who had grade 2 or greater cervical intraepithelial neoplasia on endocervical sampling compared to those who did not. The overall prevalence of high-grade dysplasia in endocervical samples in women with less than high-grade screening Pap results was 5.3%. For all entries, 4.2% (126/3026) had grade 2 or greater cervical intraepithelial neoplasia on endocervical sampling that would not otherwise have been identified. This study demonstrates that endocervical sampling has diagnostic utility in the setting of less than high-grade referral Pap smears. No benefit was demonstrated in patients with normal cytology and high-risk strains of human papillomavirus identified on referral Pap. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index