| Autor: |
Hindar, Camilla, Chang, Yu‐Mei, Syme, Harriet M., Jepson, Rosanne E. |
| Předmět: |
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| Zdroj: |
Journal of Veterinary Internal Medicine; Nov2020, Vol. 34 Issue 6, p2516-2524, 9p |
| Abstrakt: |
Background: Cats with chronic kidney disease (CKD) have an increased prevalence of positive urine cultures (PUC). Limited information is available regarding the prognosis of cats with CKD and concurrent PUC. Objective: To determine the association of PUC with survival time and disease progression in cats with CKD. Animals Medical records of 509 cats diagnosed with azotemic CKD between 1997 and 2018. Methods: Cats were classified as having "no‐PUC" or "PUC." The PUC cats were further classified as having 1 or multiple PUC, and also were classified based on the presence or absence of clinical signs of urinary tract infection (UTI). Progression of CKD was defined as a plasma creatinine concentration increase of ≥25% within 365 days of CKD diagnosis; PUC also must have occurred within this time frame. Survival time and frequency of CKD progression were compared between groups. Results: No significant difference in survival time was found between cats with no‐PUC and cats with any number of PUC (P =.91), or between cats with no‐PUC, 1 PUC or multiple PUC (P =.37). Also, no significant difference was found in the frequency of CKD progression between PUC and no‐PUC cats (P =.5), or among no‐PUC, 1 PUC and multiple PUC cats (P =.22). When assessing cats with clinical signs of lower UTI, no significant difference was found in the frequency of CKD progression between cats with true UTI, subclinical bacteriuria or no‐PUC (P =.8). Conclusions and Clinical Importance: When treated with antibiotics, PUC in cats with CKD do not affect disease progression or survival time. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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