Candida Rugosa Lipase-catalyzed Kinetic Resolution of 3-(Isobutyryloxy)methyl 4-[2-(Difluoromethoxy)phenyl]-2-methyl-5,5-dioxo-1,4-dihydrobenzothieno[3,2-b]pyridine-3-carboxylate.

Autor: Sobolev, A., Zhalubovskis, R., Franssen, M. C. R., Vigante, B., Chekavichus, B., Duburs, G., de Groot, Ae.
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds; Jul2004, Vol. 40 Issue 7, p931-937, 7p
Abstrakt: The lipase-catalyzed kinetic resolution of 3-(isobutyryloxy)methyl 4-[2-(difluoromethoxy)phenyl]-2-methyl-5,5-dioxo-1,4-dihydrobenzothieno[3,2-b]pyridine-3-carboxylate has been performed. The most enantioselective reaction (E = 28) was transesterification with n-butanol in water-saturated toluene at 45°C. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index