ID 139. Amlodipine Induced Gingival Hyperplasia in Military Personnel: A Case Report.

Autor: Gill A/L Baldev Singh, Manvikram Singh, Ahmad Noor, Tengku Natasha Eleena Tengku, Zakaria, Ainul Zawanah, Zakaria, Ahmad Nazrin, Zamri, Mohd Amir Ehsan, Basari, A. Halim Hj
Předmět:
Zdroj: Journal of Pharmacy & Bioallied Sciences; 2020 Supplement, Vol. 12, p899-900, 2p
Abstrakt: Introduction: Malaysian Armed Forces military personnel undergo routine healthcare assessment. The Armed Forces Medical Administration and Technical Instructions (AFMATI) define this into PULLHEEMS Employment Standard and DENTAP dental readiness. Assessment requires Medical Officer (MO), Dental Officer (DO) and pharmacist's multidisciplinary expertise. Objective: This is a case report of a 29 years old Royal Malaysian Air Force male corporal who reported for assessment. He has history of hypertension and is taking tablet amlodipine 10 mg daily. Materials and Methods: On intraoral examination, marginal and interdentally gingival enlargement was covering almost coronal one-third of maxillary and mandible anterior teeth. Gingival was pink in color with erythematous area and lobule surface. Margins were rolled out with loss of normal gingival scalloping. On palpitation, gingival was firm and resilient in consistency. Results: The DO performed a session of debridement with scaling, advised for regular oral hygiene and case was referred to the MO. MO discussed with the pharmacist and agreed with suggestion to replace amlodipine with tablet perindopril 8mg daily. Significant changes were noticed after one month. Gingival hyperplasia is one of the side effects associated with calcium channel blockers. Pathogenesis is categorized into inflammatory and non-inflammatory pathway. It can be treated with scaling, root planning, drug substitution, surgical excision, maintenance and supportive therapy. Conclusion: Drug induced gingival hyperplasia is rarely reported in Malaysia due to lack of coordination between health care professionals in the health care system. The multidisciplinary team approach in assessing military personnel is fundamental in preventing or detecting and minimizing non-combat casualties. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index