| Autor: |
Mamat, Ruzmayuddin, Singh, Darshan Singh Mahinder, Yusoff, Nursazreen Amalina Mohamad, Nasrulddin, Nor Afiqah Ahmad |
| Předmět: |
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| Zdroj: |
Journal of Pharmacy & Bioallied Sciences; 2020 Supplement, Vol. 12, p861-861, 1/3p |
| Abstrakt: |
Introduction: Studies investigating the misuse of illicit substances among patients in Methadone Maintenance Treatment (MMT) programs are still limited. Objectives: This study aimed to determine the association of methadone dose with illicit substance misuse among methadone patients in government MMT programs in Kuantan, Pahang. Materials and Methods: This crosssectional study was conducted at nine MMT clinics in Kuantan, Pahang between January and December 2018. Convenience and snowball sampling were utilised in recruiting the study participants. Active patients with >6 weeks in treatment and >18 years old were the inclusion criteria in this study. Psychiatric patients and in induction phase were excluded. A validated questionnaire was used to collect all required data. The socio-demographic data was descriptively analysed, while Chi-square test was applied for other data analysis. Results: A total number of 237 patients enrolled in this study. Majority were males (97%, n=230/237), while most were Malays (96%, n= 228/237), 53% married (n=125/237), and 83% (n=198/237) were employed. Mean duration of treatment was 48.86 months and average methadone dose was 52.7mg/daily. 55% (n=130/237) of respondents were received ≤50mg of methadone dose daily. Low methadone dose (≤50mg/daily) was found to be significantly associated with opiate use in the last 30 days (OR: 0.3: 0.19-0.59; p<0.000). Meanwhile, high methadone dose (>50mg/daily) was associated with opiate injection in the last 30 days (OR: 5.6: 1.72-18.22; p<0.002). Conclusion: Since low methadone prescription (≤50mg/daily) was associated with illicit drug use. An optimum methadone maintenance dose >60mg together with psychosocial intervention are deem appropriate to reduce use of illicit opiates. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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