Dietary Total Antioxidant Capacity and Risk of Non-Alcoholic Fatty Liver Disease: A Case-Control Study.

Autor: Salehi-Sahlabadi, Ammar, Mokari, Amin, Elhamkia, Maryam, Farahmand, Fariba, Jabbari, Masoumeh, Hekmatdoost, Azita
Zdroj: Journal of Research in Health Sciences; Summer2020, Vol. 20 Issue 3, p1-6, 6p
Abstrakt: Background: Dietary total antioxidant capacity (DTAC) has been proposed as a tool for assessing the intake of antioxidants. This study aimed to assess whether a relationship exists between dietary total antioxidant capacity (TAC) and the odds of NAFLD. Study design: A case-control study. Methods: In this age-and sex-matched case-control study in 2019, patients with NAFLD and healthy controls were recruited from a hospital clinic. All participants completed a validated 168- item food frequency questionnaire, the results of which were subsequently used to generate dietary TAC. Oxygen radical absorbance capacity values were used to calculate dietary TAC. Results: Altogether, 225 patients with NAFLD and 450 healthy controls were enrolled. Participants with NAFLD had a higher mean weight, BMI, energy (P<0.050), and lower physical activity and DTAC scores (P<0.050) than the control group. In an adjusted model, participants who were in the highest quartile of dietary TAC had a lower risk of NAFLD (odds ratio 0.78, 95% CI: 0.67, 0.91). Conclusion: A high DTAC was related to a decreased risk of NAFLD. Suggest the intake of a diet with high antioxidant capacity is significant at preventing NAFLD. Increasingly itemized investigations in design of randomized control trials require to reveal more insight into these results. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index