| Autor: |
Kane, Ali M., Baiee, Falah H., Najem, Eqbal S. |
| Předmět: |
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| Zdroj: |
Biochemical & Cellular Archives; 2020Supplement2, Vol. 20, p3715-3721, 7p |
| Abstrakt: |
Rue (Ruta graveolens L.) is a medicinal plant that despite the anti-androgenic effects is currently used for treatment of various disorders. This study was conducted to investigate the effects of dietary supplementation of the Rue (R. graveolens L.) extract (1, 10 and 100 mg/kg in feed) on the courtship behaviors and sexual hormones of adult male guppy (Poecilia reticulate) for 30 days. Fish were fed 100 mg/kg Rue extract that showed a significant increase in 17 â-estradiol (E2) level, while the testosterone (T) level and the ratio of T/E2 were significantly decreased compared to the control group. Furthermore, Rue dietary significantly decreased the courtship behaviors in the male guppy in a dose-depended manner. The males at the highest dose group (100 mg/kg) showed less copulation attempts, in compare to control males. In addition, times spent in sigmoid display and with the females were significantly decreased in the males fed diets containing 10 and 100 mg/ kg of Rue extract. Furthermore, there was a positive correlation between courtship behaviors and T level, while negatively correlated with E2 concentrations. In conclusion, these results indicate that R. graveolens acts as anti-androgenic endocrine disruptor, and adversely affected the courtship behaviors and sex hormones of maleguppy, which can result in impaired reproduction. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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