SYNTHESIS AND CHARACTERIZATION OF NEW METHYL-7- HYDROXYCOUMARIN-3-ACETYL DERIVATIVES.

Autor: Al-Mohammedi, Mohammad Hameed, Mohammad, Abdul Karim-Talaq, Husain Al-Majidi, Suaad Mohammed, Zughair, Mohammad
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Zdroj: Biochemical & Cellular Archives; 2020Supplement2, Vol. 20, p3383-3393, 11p
Abstrakt: A new seris from 3-acetyl-2-oxo-2H-chromen-7-yl (4-Alkyloxy) benzoate derivatives have been synthesized. Coumarin wase prepared by the reaction between 2, 4-dihydroxybenzaldehyde and ethyl acetoacetate in the presence of piperidine.a Another intermediates compounds 4-(Alkyloxy) benzoic acid were prepared by aWilliams on ether synthetic, from reaction between 4-Hydroxybenzoic acidand bromo alkane. The series of titled compounds (3a-i)3-acetyl-2-oxo-2H-chromen-7-yl (4- Alkyloxy) benzoate have been synthesized by esterification reaction between compound 1 and series of compounds 2a-i, to give the series of compounds 3a-i. All the synthesized compounds were characterized through their physical properties and diagnosed by using FTIR, 1H NMR and 13 CNMR spectrophotometric. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index