RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer.
| Autor: | Church, R. D., Yu, J., Fleshman, J. W., Shannon, W. D., Govindan, R., McLeod, H. L. |
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| Předmět: |
COLON cancer
CYCLOOXYGENASES RNA CARCINOGENESIS METASTASIS CANCER invasiveness BACTERIOPHAGE typing COLON tumors COMPARATIVE studies DNA probes INTESTINAL mucosa ISOENZYMES RESEARCH methodology MEDICAL cooperation MEMBRANE proteins NUCLEOTIDES OXIDOREDUCTASES POLYMERASE chain reaction RECTUM tumors REFERENCE values RESEARCH SURVIVAL analysis (Biometry) TIME TUMOR classification EVALUATION research |
| Zdroj: | British Journal of Cancer; 9/13/2004, Vol. 91 Issue 6, p1015-1018, 4p |
| Abstrakt: | Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles they play in established tumours of similar stage remains unclear. We report that Cox-1 and Cox-2 expression is highly variable in Dukes' C tumours, and changes in Cox-1 expression may be of importance. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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