| Autor: |
Iizuka, Ai, Ishii, Kenji, Wagatsuma, Kei, Ishibashi, Kenji, Onishi, Airin, Tanaka, Mika, Suzuki, Hiroyuki, Awata, Shuichi, Fujiwara, Yoshinori |
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| Zdroj: |
Aging Clinical & Experimental Research; Nov2020, Vol. 32 Issue 11, p2349-2355, 7p |
| Abstrakt: |
Background: Influence of cognitive intervention programs on brain activity has not been enough explored. Aims: The aims of the present study were to clarify changes in brain activity from a cognitive intervention program utilizing the board game "Go" and to examine the relationship between brain activity and the acquisition of Go skills. Methods: Eighteen community-dwelling older adults were randomly assigned either to an intervention group (IG), in which members attended 12 Go lessons either in groups or individually using tablet computers, or a control group (CG), in which members attended health education lectures unrelated to Go. Fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET), cognitive assessments, and Go tests were performed before and after the intervention. Results: The results showed different patterns of regional FDG uptake in both groups: regional cerebral glucose metabolism was significantly increased in the left middle temporal gyrus (MTG) and bilateral putamen (p < 0.01; cluster level) in the IG, and in the left superior frontal gyrus in the CG, (p < 0.01; cluster level). Furthermore, Go test scores were significantly improved in the IG (p < 0.05), and a significant association was observed between changes in Go test scores and glucose metabolism in the left MTG (p < 0.05). Conclusions and discussion: This study indicates that a cognitive intervention program using Go may enhance brain activity. Further studies with larger populations and longer observation periods are needed to clarify the neural mechanisms underlying our Go intervention program. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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