| Autor: |
Kalm‐Stephens, Pia, Nordvall, Lennart, Janson, Christer, Neuman, Åsa, Malinovschi, Andrei, Alving, Kjell, Kalm-Stephens, Pia |
| Předmět: |
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| Zdroj: |
Acta Paediatrica; Nov2020, Vol. 109 Issue 11, p2324-2331, 8p |
| Abstrakt: |
Aim: To investigate the independent relationships between baseline characteristics and incident wheeze in adolescents, with particular regard to gender.Methods: Adolescents (N = 959), aged 12-15 years, answered a standardised respiratory questionnaire and underwent height and weight measurements at baseline. Four years later, 96% of the subjects completed a similar questionnaire. The present study included the adolescents without self-reported wheeze at baseline (n = 795; 394 girls).Results: The proportion of adolescents with obesity was higher among subjects with incident wheeze than among subjects who never reported wheeze: 19.1% vs 8.3%. When stratifying for gender, this difference was only found in girls. In stepwise logistic regression models (odds ratios [95% confidence interval]), obesity (2.84 [1.17-6.86]) and rhinitis (3.04 [1.53-6.03]) at baseline and current smoking (2.60 [1.16-5.82]) at follow-up were associated with incident wheeze in girls. For boys, FEV1 <-1.65 standard deviation (3.20 [1.04-9.79]), family asthma (3.16 [1.46-6.86]) and seasonal allergic symptoms (5.61 [2.56-12.27]) at baseline were independently associated with incident wheeze.Conclusion: Data stratified by gender showed that obesity in girls and an atopic constitution in boys were independently associated with increased risk of developing wheeze within four years. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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