| Autor: |
Ghedira, Hela, Radhouane, Khaled, Mezni, Essia, Yahiaoui, Safia, Stambouli, Hela, Yedeas, Mohamed Dehmani, Belaid, Asma, Ammar, Chiraz, Kacem, Karima, Zriba, Samy, Msadek, Fehmi, Yedeas, Mondher, Harbaoui, Ahmed, Chkili, Ridha |
| Předmět: |
|
| Zdroj: |
Surgical Neurology International; 10/21/2020, Vol. 12, p1-5, 5p |
| Abstrakt: |
Background: Various hematological malignancies, including multiple myeloma, plasmacytoma, aggressive lymphoma, and indolent lymphoma, rarely result in spinal cord compression. Methods: Here, we retrospectively analyzed 32 patients with multiple myeloma (50%), plasmacytoma (13%), aggressive lymphoma (28%), and indolent lymphoma (9%), resulting in spinal cord compression (2004 and 2016). Patients averaged 57 years of age and presented with the indolent onset of spinal cord compression (91% of cases) resulting mostly in motor deficits (69%). Results: Local treatment modalities included radiotherapy (RT) (28%) alone, decompressive surgery (28%) alone, or decompressive surgery with consolidation RT (40%). The 1-year overall survival was 70%, and the progressionfree survival frequency was 62%. Conclusion: This study highlighted the importance of standardizing the indications for RT alone versus RT with surgery depending on the patient's underlying pathological diagnosis, neurological deficits, and radiological findings. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
