| Autor: |
Syaify, Ahmad, Anggraini, Paramitha Dewi, Adianti, Raudya Paramitha, Sari, Rezmelia |
| Předmět: |
|
| Zdroj: |
Indian Journal of Public Health Research & Development; Apr2020, Vol. 11 Issue 4, p540-546, 7p |
| Abstrakt: |
Background: Wound healing process is needed to restore the anatomical structure and physiological functions of the damaged tissue. The inflammatory phase in the wound healing process is characterized by the recruitment of neutrophil, macrophages and lymphocytes cells to the lesion site. Wound healing can be accelerated with PRF and amniotic membranes that can be used as dressings. These membranes have their respective strengths and weaknesses. This study aims tocomparethe inflammatory phasein the healing process of open wounds after the application of these two membranes. Method: The subject of this study consisted of 36 males Oryctolagus cuniculus which, given a wound to the labial gingival of mandibular central incisors with deepitelization method. Subjects were divided into group I which applied to the PRF releasate membrane, group II, which applied with amniotic membrane and group III which not applied with both membranes. Three subjects were decapitated from each group on the 1st, 3 rd, 5th and 7th day. The number of neutrophils, macrophages and lymphocyte cells were observed with a light microscope equipped with Optilab Viewer software, then calculated and analyzed by two-way ANOVA test followed by the LSD Post Hoc test. Results: The data of the average number of neutrophil, macrophage and lymphocyte were analyzed and shows the difference in the number of neutrophil between each group were significantly different (p<0.05). It also shows that the difference in the number of macrophages between the membrane groups and control group was significantly different (p <0.05), but the number of macrophages between group the membrane groups was not significantly different (p >0.05). Lastly, it shows the difference in the number of lymphocytes between each group were significantly different (p <0.05). Conclusion: Growth factors contained in amniotic membrane and PRF membrane release can suppress inflammatory cells, so the inflammatory phase takes place faster than physiologically. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
