| Autor: |
Ridha, Nadirah Rasyid, P, Nurhudayah Jamaluddin A., Daud, Dasril |
| Předmět: |
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| Zdroj: |
Indian Journal of Public Health Research & Development; Jul2020, Vol. 11 Issue 7, p1384-1390, 7p |
| Abstrakt: |
Background. The increasing rate of morbidity and mortality in leukemic patients are frequently found in hyperleukocytosis state. Hyperleukocytosis is defined by a white blood cell count more than 50.000/mm3. Hyperleukocytosis still becomes an oncologic emergency that need immediate treatment. The complications that will develop if it is not immediately treated is hemostatic disorder such as intracranial bleeding and pulmonal bleeding. Objective. This study aimed to assess the differentiation of hemostatic parameters between ALL-L1 with hyperleukocytosis and without hyperleukocytosis Methods. The study was a cross sectional study at conducted in DR. Wahidin Sudirohusodo Hospital from November 2016 to April 2017 with seventy-two patients aged 1 month-18 years old were diagnosed with ALL-L1 based on BMP result. They were divided into two groups, 31 patients with hyperleukocytosis and 41 without hyperleukocytosis. Then they were assessed by hemostastic parameters laboratory examination (Platelet, PT, APTT, D-Dimer, and Fibrinogen). Result. There was no significant difference in platelet count, PT, APTT, D-Dimer and fibrinogen levels between ALL-L1 patients with hyperleukocytosis and without hyperleukocytosis. Mean of platelet count with p value = 0.621, mean PT with p value = 0.429, mean APTT with P value = 0.918, mean D-Dimer with p value = 0.882 and mean fibrinogen with p value = 0.455. Conclusion. There was no significant difference of haemostatic parameters between ALL-L1 patients with hyperleukocytosis and without hyperleukocytosis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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