Three new muurolane-type sesquiterpene glycosides from the whole plants of Balanophora fungosa subsp. indica.

Autor: Huu Tai, Bui, Xuan Nhiem, Nguyen, Hai Yen, Pham, Hong Quang, Tran, Thi Cuc, Nguyen, Thi Trang, Do, Van Doan, Vu, Thuy Hang, Dan Thi, Van Minh, Chau, Van Kiem, Phan
Předmět:
Zdroj: Natural Product Research; Oct2020, Vol. 34 Issue 20, p2964-2970, 7p
Abstrakt: Three new muurolane type sesquiterpene glycosides, named balanoindicosides A − C (1 − 3), were isolated from the whole plant of Balanophora fungosa subsp. indica using various chromatographic methods. Their structures were determined by extensive analysis of HR-ESI-MS and NMR spectroscopy. The stereochemistry of muurolane sesquiterpene backbone was demonstrated by NOESY analysis. Configuration of C-12 in compounds 2 and 3 could be distinguished by chemical shift value of C-14. Compounds 1-3 exhibited weak cytotoxic activity towards HepG-2, HL-60, LU-1, and MCF-7 cell lines. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index